Karakterisasi dan Identifikasi Minyak Cengkeh (Syzygium Aromaticum (L.) Merry. & L.M.Perry)
DOI:
https://doi.org/10.29313/bcsp.v6i2.25870Keywords:
Minyak Cengkeh, Eugenol, AntijamurAbstract
Abstract. Oral candidiasis is a fungal infection caused by Candida albicans. Clove oil (Syzygium aromaticum (L.) Merr. & L.M. Perry) possesses antifungal activity with the potential for development as a pharmaceutical active ingredient. This study aimed to characterize the physical properties and identify the compounds present in clove oil (Syzygium aromaticum (L.) Merr. & L.M. Perry) using Gas Chromatography-Mass Spectrometry (GC-MS). Physical characterization revealed that the clove oil was a yellow liquid with a characteristic clove odor and a specific gravity of 1.0419 ± 0.0002 g/mL. Compound identification via GC-MS showed that the clove oil contained several components: eugenol (16.63%), β-caryophyllene (2.15%), bornyl chloride (1.24%), benzene, (1-pentylhexyl)- (3.09%), and benzene, (1-ethylphenyl)- (5.89%). Based on these results, clove oil contains eugenol as the primary active compound responsible for its antifungal activity.
Abstrak. Kandidiasis oral merupakan infeksi jamur yang disebabkan oleh Candida albicans. Minyak cengkeh (Syzygium aromaticum (L.) Merr. & L.M. Perry) memiliki aktivitas antijamur yang berpotensi untuk dikembangkan sebagai bahan aktif farmasi. Penelitian ini bertujuan untuk melakukan karakterisasi fisik dan identifiasi senyawa yang terkandung pada minyak cengkeh (Syzygium aromaticum (L.) Merry. & L.M.Perry) menggunakan Gas Chromatography Mass Spectroscopy (GC-MS). Hasil karakterisasi fisik menunjukan bahwa minyak cengkeh berupa cairan berwarna kuning, bau khas cengkeh dan bobot jenis sebesar 1,0419 ± 0,0002 g/mL. Hasil identifikasi senyawa menggunakan Gas Chromatography Mass Spectroscopy (GC-MS) menunjukan bahwa minyak cengkeh mengandung beberapa komponen, yaitu eugenol sebesar 16,63%, β-caryophyllene sebesar 2,15%, bornyl chloride sebesar 1,24%, benzene, (1-pentylhexyl)-) sebesar 3,09%, benzene, (1-ethylphenyl-) sebesar 5,89%. Berdasarkan hasil tersebut, minyak cengkeh mengandung eugenol sebagai senyawa aktif utama yang memiliki aktivitas antijamur.
References
Bonetti, L., Caprioglio, A., Bono, N., Altomare, L., & Candiani, G. (2023). Biomaterials Science infections †. Mc. https://doi.org/10.1039/d2bm01540d
Dewayanti, W., Kedokteran, F., & Lampung, U. (2022). Efektivitas Kunyit (Curcuma Longa Linn) Sebagai Anti Jamur. 2019–2024.
Gould, O., Nguyen, N., & Honeychurch, K. C. (2023). New Applications of Gas Chromatography and Gas Chromatography-Mass Spectrometry for Novel Sample Matrices in the Forensic Sciences : A Literature Review.
Ilmiah, J., & Pendidikan, W. (2024). Analisis Komponen Senyawa Minyak Atsiri dalam Tumbuhan dengan Menggunakan Metode GC-MS. 10(13), 475–492.
Kamatou, G. P., Vermaak, I., & Viljoen, A. M. (2012). Eugenol—From the Remote Maluku Islands to the International Market Place: A Review of a Remarkable and Versatile Molecule. 6953–6981. https://doi.org/10.3390/molecules17066953
Kemenkes RI VI, E. (2020). INDONESIA.
Khalifea, H. H., & Ali, N. M. (2025). Exploring the Principles of GC-MS : Techniques and Applications. 3, 1–10.
Kim, T., Tran, N., Tran, T. H., Le, X. T., Toan, T. Q., Trang, T., Ngoc, L., Le, H., Anh, T., & Cang, M. H. (2020). Journal of Global Pharma Technology Effect of Storage Conditions on the Chemical Composition of Vietnamese Clove ( Syzygium aromaticum ) Essential Oil. 447–454.
Liñ, R., Aghababaei, F., Rodr, S., Hasiri, Z., & Ziogkas, D. (2024). Clove Essential Oil : Chemical Profile , Biological Activities , Encapsulation Strategies , and Food Applications. 1–38.
Maji, S. R., Roy, C., & Sinha, S. K. (2023). Gas chromatography – mass spectrometry ( GC-MS ): a comprehensive review of synergistic combinations and their applications in the past two decades. 5(2), 72–85. https://doi.org/10.48402/IMIST.PRSM/jasab-v5i2.40209
Marwati, E., Sadik, F., Farmasi, P. S., Kedokteran, F., Khairun, U., & Leaf, C. (2025). Analisis Profil Minyak Daun Cengkeh ( Syzygium aromaticum ) Asal Kelurahan Afe Taduma Kota Ternate. 8(1), 111–118.
Online, V. A., Khalil, A. A., Sahar, A., Mehmood, T., & Khan, M. (2017). RSC Advances techniques and nutraceutical perspectives. 32669–32681. https://doi.org/10.1039/c7ra04803c
Puspitasari, A., Kawilarang, A. P., Ervianti, E., Mahasiswa, S., Dokter, P., Mikrobiologi, D., Staf, D., Fungsional, M., & Kesehatan, I. (2016). Profil Pasien Baru Kandidiasis ( Profile of New Patients of Candidiasis ).
Sumarsono, J., & Iskandar, M. N. (2025). Quality Characteristics of Clove Leaf Essential Oil Based on Leaf. 12(01), 1–8.
Xu, J. G., Liu, T., Hu, Q. P., & Cao, X. M. (2016). Chemical composition, antibacterial properties and mechanism of action of essential oil from clove buds against staphylococcus aureus. Molecules, 21(9), 1–13. https://doi.org/10.3390/molecules21091194
