Kajian Literatur Aktivitas Antioksidan Emulsi Mengandung Minyak Biji Raspberry (Rubus idaeus L.)
DOI:
https://doi.org/10.29313/bcsp.v6i2.25515Keywords:
Antioxidant Activity, DPPH, Raspberry Seed Oil.Abstract
Abstract. Raspberry seed oil (Rubus idaeus L.) is a natural ingredient with antioxidant potential that can be formulated into an emulsion system to support its use in pharmaceutical and cosmetic preparations. This article aims to examine the antioxidant activity of emulsions containing raspberry seed oil, with a focus on the Inhibitory Concentration 50 (IC₅₀) value, using a narrative-descriptive approach based on scientific articles from 2019–2026 obtained through Google Scholar, PubMed, and ScienceDirect. The literature analyzed includes studies on the antioxidant activity of raspberry seed oil as well as emulsion or nanoemulsion systems containing raspberry seed oil. The results of the study show that raspberry seed oil exhibits varying levels of antioxidant activity, both in its pure form and after being incorporated into emulsion systems. Differences in antioxidant activity and IC₅₀ values are influenced by oil concentration, formulation characteristics, formula composition, testing methods, sample preparation and testing conditions. The emulsion system may potentially affect the antioxidant activity of raspberry seed oil, but comparisons of IC₅₀ values across studies are still limited by differences in methods and experimental conditions. Therefore, standardization of testing methods is necessary to obtain more accurate comparisons of antioxidant activity.
Abstrak. Minyak biji raspberry (Rubus idaeus L.) merupakan bahan alam yang berpotensi sebagai antioksidan dan dapat dikembangkan dalam sistem emulsi untuk mendukung penggunaannya dalam sediaan farmasi dan kosmetik. Artikel ini bertujuan untuk mengkaji aktivitas antioksidan emulsi mengandung minyak biji raspberry dengan fokus pada nilai Inhibitory Concentration 50 (IC₅₀) serta faktor yang memengaruhi perbedaan aktivitas antioksidan. Kajian literatur dilakukan secara naratif-deskriptif terhadap artikel ilmiah tahun 2019–2026 yang diperoleh melalui Google Scholar, PubMed, dan ScienceDirect. Literatur yang dianalisis meliputi penelitian mengenai aktivitas antioksidan minyak biji raspberry serta sistem emulsi atau nanoemulsi yang mengandung minyak biji raspberry. Hasil kajian menunjukkan bahwa minyak biji raspberry memiliki aktivitas antioksidan yang bervariasi pada minyak maupun setelah dikembangkan dalam sistem emulsi. Perbedaan aktivitas antioksidan dan nilai IC₅₀ dipengaruhi oleh konsentrasi minyak, karakteristik sediaan, komposisi formula, metode pengujian, preparasi sampel, dan kondisi pengujian. Sistem emulsi berpotensi memengaruhi aktivitas antioksidan minyak biji raspberry, tetapi perbandingan nilai IC₅₀ antarpenelitian masih terbatas oleh perbedaan metode dan kondisi eksperimental. Oleh karena itu, standardisasi metode pengujian diperlukan untuk memperoleh perbandingan aktivitas antioksidan yang lebih akurat.
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