Studi Literatur : Aktivitas Antioksidan pada Daun Mint (Mentha Piperita L.)
DOI:
https://doi.org/10.29313/bcsp.v6i2.25213Keywords:
Mentha piperita L., Peppermint leaves, AntioxidantAbstract
Abstract. Mentha piperita L. leaves contain various bioactive compounds, including monoterpenes, flavonoids, and phenolic compounds, which exhibit promising natural antioxidant activity. This study aimed to review the antioxidant activity of Mentha piperita L. leaves using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay through a literature review approach. Literature published between 2010 and 2025 was selected based on predefined inclusion criteria. The reviewed data included extraction methods, extraction solvents, bioactive compounds, and IC₅₀ values. The findings indicated that the antioxidant activity of M. piperita was influenced by extraction methods, solvent polarity, and bioactive compound composition. Hydrodistillation generally produced essential oils rich in monoterpenes, whereas maceration using polar solvents was more effective in extracting phenolic and flavonoid compounds. The reported IC₅₀ values ranged from 2.99 mg/mL to >800 µg/mL, indicating that extraction methods, chemical composition, and environmental factors contributed to differences in antioxidant activity. Overall, Mentha piperita L. leaves have considerable potential as a natural source of antioxidants.
Abstrak. Daun mint (Mentha piperita L.) merupakan tanaman herbal yang mengandung berbagai senyawa bioaktif, seperti monoterpen, flavonoid, dan senyawa fenolik yang berpotensi sebagai antioksidan alami. Artikel ini bertujuan untuk mengkaji aktivitas antioksidan daun Mentha piperita L. menggunakan metode 2,2-diphenyl-1-picrylhydrazyl (DPPH) melalui pendekatan literature review. Penelusuran literatur dilakukan terhadap artikel penelitian yang dipublikasikan pada tahun 2010–2025 sesuai kriteria inklusi. Data yang dikaji meliputi metode ekstraksi, jenis pelarut, senyawa bioaktif, dan nilai IC₅₀. Hasil kajian menunjukkan bahwa aktivitas antioksidan daun M. piperita dipengaruhi oleh metode ekstraksi, kepolaran pelarut, serta komposisi senyawa bioaktif. Hidrodistilasi umumnya menghasilkan minyak atsiri yang kaya senyawa monoterpen, sedangkan maserasi dengan pelarut polar lebih efektif mengekstraksi senyawa fenolik dan flavonoid. Nilai IC₅₀ yang dilaporkan bervariasi, yaitu berkisar antara 2,99 mg/mL hingga >800 µg/mL, yang menunjukkan adanya pengaruh metode ekstraksi, komposisi kimia, dan faktor lingkungan terhadap aktivitas antioksidan. Secara keseluruhan, daun Mentha piperita L. berpotensi dikembangkan sebagai sumber antioksidan alami.
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