Hubungan Antara Hipertensi dengan Stroke Berulang di RS Al-Islam Bandung

  • Farras Nur Muhamad Prodi Pendidikan Dokter, Fakultas Kedokteran, Universitas Islam Bandung, Indonesia
  • Ratna Dewi Indi Astuti
  • Ismawati Prodi Pendidikan Dokter, Fakultas Kedokteran, Universitas Islam Bandung, Indonesia
Keywords: Hipertensi, Stroke Iskemik Berulang, Stroke Perdarahan Berulang

Abstract

Abstract. Recurrent stroke is a condition where an individual experiences multiple stroke attacks after having previously suffered a stroke. Uncontrolled risk factors can be significant triggers for recurrent stroke, including hypertension. This study aims to explore the relationship between hypertension and recurrent stroke, whether ischemic or hemorrhagic stroke. The research methodology employed is an analytical observational study with a case-control approach. A total of 180 respondents participated in this study, comprising 30 cases of recurrent ischemic stroke, 30 cases of recurrent hemorrhagic stroke as the case group, and 60 patients each of non-recurrent ischemic and hemorrhagic stroke as the control group. Sampling was conducted using non-probability sampling techniques, employing quota sampling for the case group and stratified random sampling for the control group. Data collection involved the observation of medical records to obtain a history of hypertension and recurrent stroke events. Data analysis was performed using chi-square tests and odds ratios to assess the level of hypertension risk associated with recurrent stroke events. The research findings indicate a significant relationship between hypertension and recurrent ischemic stroke (ρ value < α, ρ = 0.002842, OR = 4.03), while no significant association was found between hypertension and recurrent hemorrhagic stroke (ρ value > α, ρ = 0.05239, OR = 2.444). In conclusion, this study confirms the significant role of hypertension in increasing the risk of recurrent ischemic stroke. However, there is no significant relationship between hypertension and recurrent hemorrhagic stroke.

Abstrak. Stroke berulang merupakan kondisi di mana seseorang mengalami serangan stroke lebih dari sekali setelah sebelumnya telah mengalami stroke. Faktor-faktor risiko yang tidak terkontrol dapat menjadi pemicu utama terjadinya stroke berulang, di antaranya adalah hipertensi. Penelitian ini bertujuan untuk mengeksplorasi hubungan antara hipertensi dan kejadian stroke berulang, baik itu stroke iskemik maupun perdarahan. Metode penelitian yang digunakan adalah penelitian observasional analitik dengan pendekatan case-control. Sebanyak 180 responden terlibat dalam penelitian ini, dengan 30 pasien stroke iskemik berulang, 30 pasien stroke perdarahan berulang sebagai kelompok kasus, dan 60 pasien stroke iskemik serta 60 pasien stroke perdarahan yang tidak mengalami kejadian berulang sebagai kelompok kontrol. Pengambilan sampel menggunakan teknik non-probability sampling dengan quota sampling untuk kelompok kasus dan stratified random sampling untuk kelompok kontrol. Data dikumpulkan melalui observasi rekam medis untuk mendapatkan riwayat hipertensi dan kejadian stroke berulang. Analisis data dilakukan menggunakan uji chi-square dan odds ratio untuk menilai tingkat risiko hipertensi terhadap kejadian stroke berulang. Hasil penelitian menunjukkan adanya hubungan antara hipertensi dan kejadian stroke iskemik berulang (ρ value < α, ρ = 0,002842, OR = 4,03), namun tidak terdapat hubungan yang signifikan antara hipertensi dan kejadian stroke perdarahan berulang (ρ value > α, ρ = 0,05239, OR = 2,444). Kesimpulannya, penelitian ini menegaskan bahwa hipertensi berperan penting dalam meningkatkan risiko kejadian stroke iskemik berulang. Meskipun demikian, tidak terdapat hubungan yang signifikan antara hipertensi dan kejadian stroke perdarahan berulang.

References

McGraw Hill Medical. McGraw Hill Medical. Harrison Internal Medicine. 2022;21e

Dr Ppnam K. S. World Health Organization. World Stroke Day. 2021

J. E. Tintinally. Tintinalli’s Emergencu Medicine. 2020;167. 2021

World Stroke Organization (WSO): Global Stroke Fact Sheet 2022

Kementrian Kesehatan Republik Indonesia. Laporan Nasional Riset Kesehatan Dasar. RISKESDAS. 2018

Hui C, Tadi P, Patti L. Ischemic Stroke. 2022 Jun 2; 1–14

Boehme AK, Esenwa C, Elkind MSV. Stroke Risk Factors, Genetics, and Prevention. Circ Res. 2017 Feb 3;120(3):472–95.

Sedunia HH, Hartono B. HIPERTENSI: THE SILENT KILLER.

Kolmos M, Christoffersen L, Kruuse C. Recurrent Ischemic Stroke – A Systematic Review and Meta-Analysis. Journal of Stroke and Cerebrovascular Diseases. 2021 Aug;30(8):105935.

Han J, Mao W, Ni J, Wu Y, Liu J, Bai L, et al. Rate and Determinants of Recurrence at 1 Year and 5 Years After Stroke in a Low-Income Population in Rural China. Front Neurol. 2020 Jan 23;11:2.

American Stroke Association. About Stroke. 2023

Kuriakose D, Xiao Z. Pathophysiology and Treatment of Stroke: Present Status and Future Perspectives. Int J Mol Sci. 2020 Oct;21(20):1–24

Tsao CW, Aday AW, Almarzooq ZI, Alonso A, Beaton AZ, Bittencourt MS, et al. Heart Disease and Stroke Statistics-2022 Update: A Report from the American Heart Association. 2022 Feb 22;145(8):E153–639

McGraw Hill Medical. McGraw Hill Medical. Harrison Internal Medicine. 2022;21e

American Heart Assosiation 2016

Kleindorfer DO, Towfighi A, Chaturvedi S, Cockroft KM, Gutierrez J, Lombardi-Hill D, et al. 2021 Guideline for the prevention of stroke in patients with stroke and transient ischemic attack; A guideline from the American Heart Association/American Stroke Association. 202;52:E364–467.

Williams B, Mancia G, Spiering W, Rosei EA, Azizi M, Burnier M, et al. 2018 ESC/ESH Guidelines for themanagement of arterial hypertension. Vol. 39, European Heart Journal. Oxford University Press; 2018. p. 3021–104.

Primary Hypertension. 2023 Feb 10

Clinical Hypertension Eleventh Edition.

Hegde S, Ahmed I, Aeddula NR. Secondary Hypertension. 2022 Nov

Flach C, Muruet W, Wolfe CDA, Bhalla A, Douiri A. Risk and Secondary Prevention of Stroke Recurrence: A Population-Base Cohort Study. 2020 Aug;51(8):2435–44.

Donkor ES. Stroke in the 21st Century: A Snapshot of the Burden, Epidemiology, and Quality of Life. Stroke Res Treat. 2018.

Abdu H, Seyoum G. Sex Differences in Stroke Risk Factors, Clinical Profiles, and In-Hospital Outcomes Among Stroke Patients Admitted to the Medical Ward of Dessie Comprehensive Specialized Hospital, Northeast Ethiopia. Degener Neurol Neuromuscul Dis. 2022 Oct;Volume 12:133–44.

McGraw Hill Medical. McGraw Hill Medical. Harrison Internal Medicine. 2022;21e

Leoo T, Lindgren A, Petersson J, Von Arbin M. Risk Factors and Treatment at Recurrent Stroke Onset: Results from the Recurrent Stroke Quality and Epidemiology (RESQUE) Study. 2008 Mar ;25(3):254.

Powers WJ, Rabinstein AA, Ackerson T, Adeoye OM, Bambakidis NC, Becker K, et al. 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2018 Mar 1;49(3):e46–110.

Yonata A, Satria A, Pratama P. Arif Satria Putra Pratama dan Ade Yonata | Hipertensi sebagai Faktor Pencetus Terjadinya Stroke Majority. Vol. 5. 2016.

Abdu H, Seyoum G. Sex Differences in Stroke Risk Factors, Clinical Profiles, and In-Hospital Outcomes Among Stroke Patients Admitted to the Medical Ward of Dessie Comprehensive Specialized Hospital, Northeast Ethiopia. Degener Neurol Neuromuscul Dis. 2022 Oct;Volume 12:133–44.

Annisa N. S. Faktor Risiko Kejadian Stroke pada Pasien Rawat Inap di Rumah Sakit Stroke Nasional Bukit Tinggi. 2013.

Gao J, Dai Y, Xie Y, Zheng J, Wang Y, Guo R, et al. The Association of Stage 1 Hypertension Defined by the 2017 ACC/ AHA Guideline with Stroke and Its Subtypes among Elderly Chinese. 2020.

Caroline G S, Mieke A. H. N Kembuan, Rizal Tumewah. Profil Penderitas Stroke dengan Hipertensi di Bagian Rawat Inap Neurologi RSUP Prof. DR. R. D. Kandou Manaro Periode 2013-2014 Juni. 2014

Kim SM, Woo HG, Kim YJ, Kim BJ. Blood pressure management in stroke patients. Journal of Neurocritical Care. 2020 Dec 29;13(2):69–79.

Namira S. DW, Ira M A M. MODUL EPIDEMIOLOGI PENYAKIT TIDAK MENULAR (KMS351) MODUL PERTEMUAN KE-10 Epidemiologi Penyakit Stroke. 2020.

Rowley HA. The alphabet of imaging in acute stroke does it spell improved selection and outcome? In: Stroke. Lippincott Williams and Wilkins; 2013.

Filda Izzati S, Sulistyani S, Aisyah R, Setiawan I, Kedokteran F, Muhammadiyah U, et al. HUBUNGAN HIPERTENSI DAN KADAR HEMOGLOBIN DENGAN KEJADIAN STROKE ISKEMIK BERULANG The Relationship of Hypertension and Hemoglobin Levelswith Recurrence of Ischemic Stroke.

Soewarno SA, Annisa Y. PENGARUH HIPERTENSI TERHADAP TERJADINYA STROKE HEMORAGIK BERDASARKAN HASIL CT-SCAN KEPALA DI INSTALASI RADIOLOGI RSUD Prof. Dr. MARGONO SOEKARJO. Vol. 15, MEDISAINS: Jurnal Ilmiah Ilmu-ilmu Kesehatan. 2017.

Stahmeyer JT, Stubenrauch S, Geyer S, Weissenborn K, Eberhard S. M E D I C I N E The Frequency and Timing of Recurrent Stroke An Analysis of Routine Health Insurance Data.

Ayuadiningsih, R. A. W., Trusda, S. A. D., & Rachmawati, M. (2021). Karateristik Pasien Karsinoma Ovarium Berdasarkan Gejala Klinis, Penyakit Penyerta, Komplikasi, dan Usia di Ruang Rawat Inap Rsud Al-Ihsan Bandung. Jurnal Riset Kedokteran, 1(1), 1–8. https://doi.org/10.29313/jrk.v1i1.111

Nabila Alyssia, & Nuri Amalia Lubis. (2022). Scooping Review: Pengaruh Hipertensi Terhadap Penyakit Jantung Koroner. Jurnal Riset Kedokteran, 73–78. https://doi.org/10.29313/jrk.vi.1438

Published
2024-02-12